A systems-pharmacology analysis of herbal medicines used in health improvement treatment: predicting potential new drugs and targets
A network-based analysis of the types of coronary artery disease from traditional Chinese medicine perspective: potential for therapeutics and drug discovery
Recently, computational systems biology, as new emerging discipline, has brought a new combination of computational and experimental tools to bear on the discovery and investigation of drugs. System-level understanding of pharmacological effects will help to understand how drugs work on specific pathways, on different cell types and in individual patients, thus facilitating drug discovery and development of combination therapies.
Using a variety of mathematical approaches combining with experimental validations, the current research topics of Systems Pharmacology Group led by Prof. Yonghua Wang focus on but not limit to:
(1) Computational systems biology theory and methods
(2) Study of Traditional Chinese Medicine by computational systems biology
(3) Cardiovascular computational systems biology